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Title Parathyroid hormone may mediate antihypertensive fracture risk [News Medical]
Date 2016.01.23 Hit 846

By Eleanor McDermid, Senior medwireNews Reporter


Parathyroid hormone (PTH) levels may be elevated by use of some antihypertensive agents but reduced by others, analysis of the Multi-Ethnic Study of Atherosclerosis (MESA) suggests.


The researchers found that users of loop diuretics and dihydropyridine calcium channel blockers (CCBs) had higher PTH levels than non-users. By contrast, users of thiazide diuretics had lower PTH levels than non-users.


“These associations may provide a mechanistic explanation linking use of these medications to the development of skeletal outcomes”, say Anand Vaidya (Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA) and co-researchers.


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