|Title||Parathyroid hormone may mediate antihypertensive fracture risk [News Medical]|
By Eleanor McDermid, Senior medwireNews Reporter
Parathyroid hormone (PTH) levels may be elevated by use of some antihypertensive agents but reduced by others, analysis of the Multi-Ethnic Study of Atherosclerosis (MESA) suggests.
The researchers found that users of loop diuretics and dihydropyridine calcium channel blockers (CCBs) had higher PTH levels than non-users. By contrast, users of thiazide diuretics had lower PTH levels than non-users.
“These associations may provide a mechanistic explanation linking use of these medications to the development of skeletal outcomes”, say Anand Vaidya (Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA) and co-researchers.
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